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This promotional site is intended for United Kingdom (UK) healthcare professionals and other relevant decision makers only. If you are a member of the public, please click here.

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Adverse events reporting statement can be found at the bottom of this webpage.

Resources for Healthcare Professionals (HCPs)

Speaker Bureau slides: The Importance of Considering Cardiovascular Health in Men with Prostate Cancer

Latest slide deck from Accord UK Speaker Bureau meeting series that took place in June 2025.

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Speaker Bureau slides: HERO Study

Latest slide deck from Accord UK Speaker Bureau meeting series that took place in June 2025.

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EAU 2025 Symposium Highlights Article

Symposium highlights published in the EMJ digital Journal of Urology following the Accord Symposium held during EAU congress 2025 in Madrid, Spain, 21-24 March 2025.

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Clinical Papers

Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer – N.D. Shore, et al. (2020)

The HERO study was a multinational, randomised, open-label, Phase 3 trial to evaluate the efficacy and safety of ORGOVYX®, compared to leuprorelin, in men with advanced prostate cancer.1

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Cardiovascular disease risk assessment and multidisciplinary care in prostate cancer treatment with ADT: recommendations from the APMA PCCV expert network - A. Merseburger et al. (2024)

Provides insight and guidance to improving the management of CV risk in patients with prostate cancer undergoing ADT.7

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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer – K.G Gaudian, et al. (2025)2

Gaudian, et al. explores patient-reported adherence to relugolix when combined with stereotactic body radiation therapy (SBRT) for intermediate to high-risk prostate cancer.9

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Relugolix in Combination with Androgen Receptor Pathway Inhibitors in the Treatment of Metastatic Prostate Cancer: A Clinical Perspective - T. Buchler (2025)

Buchler evaluates the pharmacokinetics, efficacy, safety and interactions of the coadministration of ORGOVYX® with androgen receptor pathway inhibitors (ARPIs) for the treatment of advanced prostate cancer.10

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Buchler et al. (2025) Clinical Paper Summary

Download the slide deck summarising real-world data on relugolix co-administered with ARPIs in metastatic prostate cancer, based on Buchler 202510

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Cirne et al. (2022) Clinical Paper Summary

Download the slide deck summarising findings on cardiovascular risks of GnRH antagonists vs. agonists from the Cirne 2022 study11

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Merseberger et al. (2024) Clinical Paper Summary

Download the slide deck outlining expert recommendations on cardiovascular risk assessment and multidisciplinary care in ADT-treated prostate cancer, from Merseburger 20247

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Nelson et al. (2023) Clinical Paper Summary

Download the slide deck summarising Nelson et al. (2023) on the cardiovascular safety of GnRH antagonists versus agonists in prostate cancer12

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Shore et al. (2020) Clinical Paper Summary

Download the slide deck summarising the efficacy and safety of oral relugolix vs leuprorelin in men with advanced prostate cancer, based on Shore et al. (2020)1

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Weiner et al. (2021) Clinical Paper Summary

Download the slide deck summarising Weiner et al. (2021) on causes of death in US men with prostate cancer, stratified by stage and demographics13

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Resources for Patients

Please do not share this page directly with patients and instead download the resources for offline use to show or share during appointments.

The Unmentionables: Online Discussion Guide

Enables your patient to answer questions to help personalise their next appointment with their healthcare team.

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The Unmentionables: Podcast

Podcast series hosted by Jeff Stelling helping people to talk openly about what matters most in prostate cancer. This podcast is for people diagnosed with prostate cancer and their families.

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ORGOVYX® is indicated for the treatment of adult patients with advanced hormone-sensitive prostate cancer; for the treatment of high-risk localised and locally advanced hormone dependent prostate cancer in combination with radiotherapy; as neo-adjuvant treatment prior to radiotherapy in patients with high-risk localised or locally advanced hormone dependent prostate cancer.8

ADT, androgen deprivation therapy; ARPI, androgen receptor pathway inhibitor; APMA, Asia Pacific Multidisciplinary Action; CV, cardiovascular; CVD; cardiovascular disease; ESC, European Society of Cardiology; ESMO, European Society for Medical Oncology; GnRH, gonadotropin-releasing hormone; HCP, healthcare professional; MCBS, magnitude of clinical benefit scale; NICE, National Institute for Health and Care Excellence; PCCV, Prostate Cancer Cardiovascular; SMC, Scottish Medicines Consortium; TA, technology appraisal.

Job code: UK---01492 | Date of preparation: January 2026